2015-03-07

Potential of genotyping-by-sequencing for genomic selection in livestock populations

Our new paper titled "Potential of genotyping-by-sequencing for genomic selection in livestock populations" has been published in Genetics Selection Evolution. This work shows that genotypes called from low-coverage sequencing data can be equally or even more powerful for genomic prediction than high-quality SNP genotypes. In particular manipulation of coverage allows us to increase number of genotyped individuals at the expense of genotype quality and this can bring us a long way before accuracy of genomic predictions falls significantly. Another useful application is in increasing selection intensity by genotyping more/all selection candidates.

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